Pathophysiology & Pharmacotherapeutics 1 – Paediatric

This course will explore the mechanism of altered functioning of human cells, organs, organ systems and the organism as a whole in the context of adult primary health care including care of older adults. Material in this course builds on previous knowledge of physiology and introductory pathophysiology. In addition, this course will provide students with knowledge of basic pharmacologic concepts, including pharmacokinetics, pharmacodynamics and pharmacotherapeutics. There will also be a focus on therapeutic interventions, including consideration of at risk populations.

The primary focus of this course is on disorders found frequently in community settings pertaining to individuals from adolescent to old age. The intention of this course is not to comprehensively address all illnesses and conditions, but rather to highlight common illnesses and provide a framework from which to organize knowledge application within any adult specialty. This framework will be based primarily around the following concepts:

  • Alteration in normal body functions which lead to illness/injury, chronic disease, comorbidities and emergency health needs
  • Systematic examination of illness manifestation
  • Clinical presentations related to pathophysiological and psychopathological changes
  • Client assessment and diagnostic formulations (differential diagnosis)
  • Recommended treatment planning, focused on pharmacotherapeutics
  • Health implications of client/population trends, including but not limited to the following topics:
    • Social determinants of health
    • Vulnerable populations
    • Basics of pharmacotherapy
    • Controlled drugs and substances use, misuse, abuse, addiction and diversion
    • Hematology Oncology
    • Infectious diseases
    • Vaccines
    • Eyes and ears
    • Mental health
    • Musculoskeletal disorders
    • Dermatology
  • Pharmacologic content, including but not limited to:
    • Drug therapy decision making
    • Drug information gathering and interpretation
    • Common indicators for prescribing various classes of controlled substances (including those related to acute/chronic/palliative pain, hyperkinetic and substance abuse, hormonal disorders, sleep disorders, and neurological conditions)
    • Development of appropriate drug monitoring plans, with consideration for at risk populations
    • Mechanisms of adverse drug reactions, drug interactions, and strategies to identify, assess and manage adverse effects of drug therapies
    • Process for reporting to appropriate authorities, in keeping with relevant legislation and organizational policies
    • Marketing strategies used to promote health products, medical devices, medications, and health programs
  • Non-pharmacological therapies including but not limited to:
    • Counselling
    • Complementary and alternative therapies in relation to various disease states
    • Complementary and alternative therapies in relation to pain management